Food Xplorer (FOX)- semi-quantitative test to determine IgG-dependent hypersensitivity to 286 food products



Food Xplorer (FOX) - semi-quantitative test to determine IgG-dependent hypersensitivity to 286 food products
Advantages:
- Nano-technology
- 286 food antigens from 13 food groups
- Main products used in our country and in the world
- Blood serum is used for the analysis
- FOX is used by:
– to clarify dietary status
– to monitor compliance with the diet
– with immunologically caused food intolerance
– for diagnosis of sensitivity to food products
– with “leaky” bowel syndrome
Main indications for the test:
- Suspicion of IgG-dependent food intolerance
- Inflammatory bowel diseases
- Irritable bowel syndrome
- Depression and migraine
Food allergy type III -
this is a delayed hypersensitivity reaction, representing a systemic reaction of the whole body involving several organ systems. Dysfunction of the gastrointestinal tract is the main factor in the pathogenesis of various systemic manifestations. Due to the high permeability of the intestinal walls, dietary proteins can cross the intestinal barrier in an unusual way, engaging the immune system and ultimately causing inflammatory reactions. Accompanying symptoms are delayed and range from gastrointestinal symptoms and joint pain to migraine. Delayed-type allergic reactions to food products are mediated by IgG antibodies. By detecting food-specific IgG antibodies in the blood serum, allergens that provoke a reaction can be easily identified and symptoms alleviated by avoiding the relevant foods.
All major sources of type III food allergy are identified using FOX.
Technology
Step 1:
adhesion of antigen extract to nanoparticles
Step 2:
adhesion to the solid phase



Різні комбінації оптимізовані для кожного продукту
analysis procedure
Preparation:
Blood sampling and serum preparation

Step 1:
Serum incubation
120 min

Wash:
Elution of unbound antibodies
3 x 5 min

Step 2:
Serum incubation
30 min

Washing
Elution of unbound antibodies
5 x 5 min

Step 3:
Enzymatic (color) reaction
5-10 min

Analysis
Image acquisition, analysis and report
< 1 min

an example of the result of the analysis


Food antigens

VEGETABLES

NUTS
almond, brazil nut, cashew, coconut, coconut milk, hazelnut, kola nut, macadamia, pecan, pistachio, sweet chestnut, chufa, walnut

BEANS

FISH AND SEAFOOD
abalone, Atlantic cod, Atlantic herring, Atlantic pink bass, carp, roe, cock, common mussel, crab, eel, European hamsa, European sardine, European flounder, golden spar, haddock, hake, lobster, mackerel, monkfish, crayfish , pike, northern shrimp, octopus, oyster, bivalve mollusk, salmon, scallop, cuttlefish, mixed shrimp, sole, squid, swordfish, sea fox, trout, tuna, turbot, venerids

EDIBLE MUSHROOMS
boletus, chanterelle, boletus, boletus, porcini mushroom, porcini mushroom


COFFEE AND TEA
chamomile, cocoa, coffee, hibiscus, jasmine, moringa, peppermint, tea (black), tea (green)

М’ЯСО
beef, wild boar meat, chicken, duck, goat meat, horse meat, lamb, ostrich meat, pork, rabbit, venison, turkey, veal, game

FRUITS
apple, apricot, banana, blackberry, blueberry, cherry, cranberry, date, elder, fig, gooseberry, grape, grapefruit, kiwi, lemon, lime, lychee, mango, melon, mulberry, nectarine, orange, papaya, passion fruit, peach, pear, physalis, pineapple, plum, pomegranate, raisin, raspberry, red currant, strawberry, tangerine, watermelon

EGGS AND MILK
buffalo milk, buttermilk, camel milk, camembert, cheese, cow’s milk, egg white, egg yolk, Emmental cheese, goat cheese, goat milk, Gouda cheese, Mozzarella cheese, Parmesan cheese, quail egg, sheep’s cheese, sheep’s milk


NEW FOOD PRODUCTS
almond milk, aloe, aronia, baobab, chia seeds, chlorella, dandelion root, ginkgo biloba, ginseng, burdock root, guarana, house cricket, maca root, mealworm, migratory locust, nori, safflower oil, spirulina, tapioca , wakame, yakon roots

SPECIES
anise, basil, bay leaf, cumin, cardamom, cayenne pepper, chili pepper (red), cinnamon, cloves, coriander, cumin, curry, dill, fenugreek, ginger, juniper berries, lemongrass, marjoram, mint, mustard, nutmeg walnut, oregano, paprika, parsley, pepper (black/ white/ green/ red/ yellow), rosemary, sage, tarragon, thyme, turmeric, vanilla

GRAINS AND SEEDS
spelt, barley, buckwheat, chickpeas, corn, durum wheat, whole wheat, double wheat, gluten, hemp, flax seeds, lupine, malt (barley), millet, oats, pine nuts, Polish wheat, poppy seeds, pumpkin seeds, quinoa, rapeseed, rice, rye, sesame, spelled, sunflower, wheat, wheat bran, wheat gliadin, wheat sprouts

OTHER
agar-agar, Aspergillus niger, baker’s yeast, brewer’s yeast, elderflowers, honey, hops, M-transglutaminase (meat glue), cane sugar, cross-reacting carbohydrate determinants